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Abnormal destructionof cells

These are relatively uncommon in the western world but elsewhere in the world are extremely important. Sickle cell disease is an important cause of ill health and anaemia in certain racial groups (see sickle cell disease). Spherocytosis is another not uncommon condition where the red cells are rounder than normal andtherefore more liable to break. There is a particular type of anaemia associated with kidney disease andthis is because of failureof production by the kidney of a hormone necessary for blood production (erythropoietin). Finally, cancers can also cause achronic anaemia, for reasons which are not understood.

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