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Severe and persistent tiredness of unknown origin. Everything about this condition is controversial starting with a query as to whether it is a single real condition at all or whether it is simply post-infectious debility. Many doctors feel that it is mainly a psychological problem; this is supported by finding that sufferers often have psychologicalor psychiatric difficulties. Theories about causation come and go; currently, theories are looking at the workings of mitochondria, components within the cell which generate power for the cell but there are not yet any scientifically agreed results from this research.

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